The Human Upgrade: Biohacking for Longevity & Performance Inflammation is Aging Your Brain – Dr. Andrew Miller : 643
Nov 12, 2019
Dr. Andrew Miller, an expert in brain-immune interactions and depression, sheds light on the alarming link between inflammation and aging in the brain. He discusses how chronic inflammation fuels major health issues, including cardiovascular disease and neurodegenerative disorders. The conversation explores the immune system's influence on mental health and the groundbreaking research on immunotherapy for depression. Miller also dives into the role of genetics, environmental factors, and potential remedies like specific supplements in managing inflammation and enhancing well-being.
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Depression from Cytokine Treatment
- Dr. Miller describes a depressed patient receiving interferon alpha for cancer treatment.
- Her depression was unrelated to the cancer itself, resembling someone with a major life disruption.
Inflammation and Aging
- Inflammation contributes to aging and many diseases.
- "Inflammaging" is a key topic, linking inflammation to cardiovascular issues, diabetes, cancer, and neurodegeneration.
Evolution of Inflammation
- Humans evolved strong inflammatory responses for survival in pathogen-rich environments.
- Interbreeding with Neanderthals and Denisovans provided genetic advantages for fighting infections outside Africa.