The Metabolic Link

Reversing Alzheimer's Disease | Dr. Dale Bredesen | The Metabolic Link Ep.74

33 snips
Aug 19, 2025
Dr. Dale Bredesen, a leading neurologist and researcher, reveals groundbreaking insights into Alzheimer’s disease. He challenges the notion of a single-cause approach, emphasizing the need for a systems-based strategy. Bredesen discusses his ReCODE Protocol, which has shown promise in reversing cognitive decline. He highlights the importance of early detection, the role of diet and toxins, and calls for a holistic approach to treatment. His insights offer hope and a proactive path forward in the fight against dementia.
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INSIGHT

Alzheimer’s Is A Network Problem

  • Alzheimer’s arises from network insufficiencies driven by energetics, inflammation, and toxicity rather than a single cause.
  • Targeting supply (metabolism, blood flow) and reducing demand (inflammation, toxins) reframes treatment strategy.
ADVICE

Start Routine Brain Biomarker Screening

  • Get blood-based brain biomarkers starting at age 35 and repeat every five years; increase frequency after 60 to every two years.
  • Use P-tau217, GFAP, and NFL together to track Alzheimer’s risk and neuronal injury.
INSIGHT

Biomarker Patterns Give Diagnostic Clues

  • GFAP signals brain inflammation or repair but is not Alzheimer's-specific; combined markers give richer diagnostic context.
  • Pattern interpretation (P-tau, GFAP, NFL) distinguishes active Alzheimer’s from other processes.
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