

The Shocking Truth About Berberine - Ford Brewer MD MPH - PrevMed Health
Oct 6, 2024
In this engaging discussion, Jesus, a physician from the PrevMed team, joins Dr. Ford Brewer to unpack the benefits and myths surrounding berberine. They explore how berberine can aid in metabolic health, cholesterol reduction, and glucose control, even comparing it to metformin. The conversation delves into berberine's potential in improving gut health and its role in inflammation markers. They also highlight practical considerations like side effects, dosing, and notable interactions with medications while shedding light on the supplement's growing market popularity.
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Berberine Has Broad Metabolic Effects
- Berberine is an isoquinolone alkaloid with broad metabolic effects including lowering glucose and cholesterol.
- It shows benefits across metabolism, inflammation, gut and liver markers but is not uniformly superior to drugs.
Clinical Effects Vs. Prescription Drugs
- Clinical trials show berberine reduces triglycerides, total cholesterol and LDL but does not outperform simvastatin.
- It lowers A1C and glucose but is not clearly better than metformin overall.
Modest Weight And PCOS Benefits
- Berberine produces modest weight and waist reductions and some PCOS hormone benefits.
- It is not consistently superior to metformin for PCOS or weight outcomes.