Everyday Wellness: Midlife Hormones, Health, and Science for Women 35+ Ep. 521 Metabolism Masterclass: Weight Loss Resistance Explained with Cynthia Thurlow, NP
Nov 19, 2025
Join Dr. William Li, an expert in metabolism, as he discusses how our metabolism evolves throughout life and the impact of various fats on our health. Michelle Shapiro, a health coach, delves into the psychological aspects of weight, including the detrimental effects of shame and adverse childhood experiences. Lara Adler, an environmental health expert, reveals how everyday chemicals can disrupt hormonal balance and lead to metabolic issues. This enlightening conversation sheds light on our health journey and offers practical insights for positive change.
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Metabolism Follows Four Life Phases
- Human metabolism follows four distinct life phases with stability from ages 20–60.
- Excess body fat suppresses metabolism rather than slow metabolism causing fat gain.
Use Lifestyle To Protect Metabolism
- Use diet and lifestyle to avoid building excess body fat and restore metabolism.
- Prioritize intermittent fasting, plant-forward foods, healthy fats, exercise, gut health, and sleep.
Brown Fat Burns Harmful Fat
- White fat stores energy while brown fat burns fuel via thermogenesis.
- Activating brown fat (and beiging white fat) helps reduce harmful visceral fat and raise metabolism.
