Everyday Wellness: Midlife Hormones, Health, and Science for Women 35+

Today, we have another episode in our series of thoughtfully curated companies. This episode is sponsored by OneSkin, a company founded and led by an all-female team of PhD-level scientists. OneSkin is redefining how we think about aging, starting with the skin, our largest organ. I am delighted to introduce Dr. Alessandra Zonari as our guest today. Dr. Zonari is far from your typical scientist. She is a true visionary with a passion for longevity, skin regeneration, and an occasional karaoke jam. With degrees in biology and stem cell biology and a doctorate in skin regeneration and tissue engineering, Dr. Zonari brings a wealth of knowledge and a fresh perspective to our conversation today. Join us to learn more about OneSkin and how their products can reverse the effects of biological aging, helping your skin become stronger and more resilient as you age. IN THIS EPISODE YOU WILL LEARN: Dr. Zonari shares her mission to understand how skin can age healthier and stronger and reduce the risk of inflammation and diseases.  How the female-led research team at OneSkin brings a unique perspective to skincare How the OneSkin peptide can reverse 2.5 years of biological aging in just five days The unique way in which they test their products and measure biological aging at OneSkin  How estradiol loss during menopause exacerbates the accumulation of senescent cells and causes inflammation Some common misconceptions about skincare for women in perimenopause and menopause How lifestyle choices influence the aging process of the skin  Why we must protect the skin from environmental stressors to slow the aging process  How your skin cells can get reprogrammed to return to a youthful state How OneSkin developed a hair care line to address hair loss and thinning The importance of self-love and nourishing your body  ABOUT OneSkin:  Founded and led by an all-woman team of PhD-level scientists, OneSkin is transforming the way we think about aging, starting with the body’s largest organ, the skin. Our proprietary OS-01 (oh ess one) peptide is the first ingredient to reverse the biological age of skin by targeting cellular senescence, a key driver of aging. By targeting cellular senescence, the OS-01 peptide switches off the damaged cells that contribute to lines, wrinkles, and sagging skin. The result? Skin that looks and behaves younger. Our products are designed for young and mature skin, because it is never too early or too late to invest in your skin health! We create next-level skin care. BIO: Alessandra Zonari, PhD, OneSkin Co-Founder & CSO Alessandra is not your typical scientist. She is a visionary with a passion for longevity, skin regeneration, and the occasional karaoke jam. Growing up in a close-knit family in Brazil, Alessandra saw her grandparents struggle with age-related diseases, and she soon became fascinated by the possibility of using stem cells to redefine the aging process. After earning degrees in biology and stem cell biology and a doctorate in skin regeneration and tissue engineering, Alessandra joined OneSkin in 2017 as a founding member and Chief Scientific Officer. Her contributions include 20+ papers, three patents, and the development of their proprietary OS-01 peptide. Connect with Cynthia Thurlow   Follow on ⁠X⁠ ⁠Instagram⁠ & ⁠LinkedIn⁠ Check out Cynthia’s ⁠website⁠ Submit your questions to ⁠support@cynthiathurlow.com⁠ Connect with Dr. Alessandra Zonari On the ONESKIN⁠ website⁠ ONESKIN on⁠ Instagram⁠ Interested in trying OneSkin for yourself? Visit⁠ oneskin.co/CYNTHIA⁠ and use code CYNTHIA for 15% off your first purchase!

Dr. Tyna Moore, a naturopathic physician and expert in regenerative medicine, shares vital insights on women's health, particularly around midlife. She discusses the dangers of under-fueling and its impact on crucial hormones, emphasizing that adequate nutrition is key for energy and strength training. Dr. Tyna also tackles societal pressures regarding body image and encourages women to prioritize muscle building for longevity and wellness. Additionally, she raises concerns about the use of GLP-1s for rapid weight loss, advocating instead for a balanced approach to fitness and nutrition.

I am honored to connect with Meg Josephson today. She is a psychotherapist holding a Master of Social Work degree from Columbia University, with a concentration in clinical practice. She is also a meditation teacher.  In our conversation, we discuss Meg's new book, Are You Mad at Me?, exploring fawning as a survival mechanism and why women are more likely to be conditioned into people-pleasing. We unpack the archetypes she refers to in her book, examining complex PTSD, and why fawners need to redefine their boundaries and acknowledge their grief and anger. Our discussion also touches on finding your voice during perimenopause and menopause, and why awareness is essential for healing. This conversation with Meg Josephson is truly invaluable, and her book is a vital resource for those who have experienced complex trauma in childhood or spent their lives people-pleasing and fawning. IN THIS EPISODE, YOU WILL LEARN: What fawning is, and why it becomes problematic if we keep on doing it when we are safe Why women and those in minority groups are more susceptible to fawning experiences  The six archetypes of people pleasers that Meg describes in her book Finding a voice to describe the experiences you grew up with Rewiring your beliefs to allow the weaknesses of your parents to become your strengths Why grief and anger are so significant for fawners Relating to your emotions rather than trying to erase them Why is it so hard for fawners to maintain their boundaries? How perimenopause and menopause provide an opportunity for women to think more introspectively How healing begins with awareness Understanding that we cannot control the perceptions of others Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Meg Josephson On social media: @ Meg Josephson Meg’s Peace of Mind Substack

Jessica Kane, the Chief Marketing Officer and co-owner of BodyBio, shares her expertise on cellular health and aging. She emphasizes the transformative role of phospholipids and essential fatty acids, explaining the differences between omega-3s and omega-6s. The conversation dives into practical testing for supporting liver and mitochondrial health, along with the potential benefits of TUDCA. Exploring innovative products aimed at gut health and aging, Jessica provides insights into how dietary choices can significantly impact overall wellness.

In this insightful conversation, Dr. Caroline Leaf, a cognitive neuroscientist and bestselling author, sheds light on how perimenopause and menopause are brain-based events. She emphasizes the importance of managing stress and the benefits of self-regulation for mental health during this transition. Dr. Leaf introduces her 5-Step Neurocycle® method for reshaping habits and discusses the implications of people-pleasing and emotional regulation. Tune in for practical strategies that empower women to navigate challenges while maintaining cognitive vitality.

I am thrilled to have Caroline Paul joining me today. She is a New York Times bestselling author, a TEDx speaker, and a longtime member of the Writers Grotto.  In our discussion, we address the issue of societal messaging about aging, the importance of bravery and resilience, and how invisibility can become a superpower as we age. We explore gender differences and the early conditioning that shapes how boys and girls perceive themselves, the power of awe for brain support, and the benefits of remaining curious and open-minded. We examine the value of novelty and neuroplasticity and unpack the five pillars of fulfilling aging: community health, new experiences, a sense of purpose, and a positive mindset about aging. Caroline also delves into her years as a firefighter, sharing how she practices being present despite being an adrenaline junkie, as well as the importance of rest and recovery. I thoroughly enjoyed today’s invaluable conversation with Caroline, and I know you will love it too! IN THIS EPISODE, YOU WILL LEARN: The types of negative messaging women receive about aging The health benefits of getting outside and being physically active Caroline shares some of her experiences as a firefighter The importance of teaching girls about bravery The value of being outside and engaging in activities that evoke awe How novelty, health, community, purpose, and a positive view of aging can help you maintain a fulfilling life Some practical advice for aging well How neuroplasticity and lifelong learning can improve your cognitive and physical health The importance of challenging societal norms and embracing adventure Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Caroline Paul On her website Instagram Caroline’s latest book, Tough Broad

I am delighted to have Dr. Ken Berry returning to the podcast for his fourth appearance today. He is a physician, bestselling author, and passionate advocate for health, known for his no-nonsense approach to wellness. Dr. Berry has practiced at the Berry Clinic since 2003 and is an active community member. He has a YouTube channel with more than 2 million subscribers- one of my favorite go-to resources for patients.  In our discussion today, we explore a recent Time news article and the growing concerns around the declining trustworthiness of media sources. We dive into the limitations of observational research, the problem with celebrity endorsements of ultra-processed foods, rising obesity rates in children and teens, and whether genetic factors are actually behind obesity, as highlighted recently in a 60 Minutes segment. We also discuss the impact of sugar, grains, and seed oils and the significance of visceral fat. You will not want to miss this invaluable discussion with Dr. Ken Berry. IN THIS EPISODE YOU WILL LEARN: Dr. Berry breaks down some deeper issues surrounding the recent Time article, where a lone registered dietician claimed that ultra-processed foods are acceptable. How media sources are losing their credibility The vital part social media plays in changing the narrative and holding media sources accountable Why consumers must stay informed and be proactive in their health choices  The health implications of eating ultra-processed foods Dr. Berry shares his concerns about the American Academy of Pediatrics recommending drugs like ozempic for children.  The benefits of eating whole foods  Dr. Berry shares his three rules for a healthy diet. Why we need to avoid sugar and seed oils How following a low-carb diet can help to reduce visceral fat. Dr. Berry introduces the American Diabetes Society and explains its mission. Bio:  Dr. Ken D. Berry, MD, is a licensed family physician, best-selling author, and leading advocate for the Proper Human Diet (PHD). With over two decades of clinical experience, Dr. Berry specializes in helping patients improve their health through low-carbohydrate, nutrient-dense eating. His best-selling book, "Lies My Doctor Told Me: Medical Myths That Can Harm Your Health," and his popular YouTube channel, which has over 3 million subscribers, provide accessible, evidence-based guidance on nutrition and wellness. Dr. Berry's mission is to empower individuals to reclaim their health by debunking common medical myths and promoting sustainable dietary and lifestyle changes. He is also a member of the Diet Doctor low-carb expert panel and an active participant in the keto and low-carb communities. Dr. Berry lives with his wife Neisha, and their children on a farm in Holladay, Tennessee. Connect with Cynthia Thurlow   Follow on  ⁠Twitter⁠ ⁠Instagram⁠ ⁠LinkedIn⁠ Check out Cynthia’s ⁠website⁠ Submit your questions to ⁠support@cynthiathurlow.com⁠ Connect with Dr. Ken Berry On his⁠ website⁠ ⁠YouTube⁠ ⁠The American Diabetes Society ⁠ Dr. Berry has three books available on Amazon:⁠ Lies My Doctor Told Me⁠,⁠ Kicking Ass After 50⁠, and⁠ Common Sense Labs

We have a follow-up from our last mashup episode on progesterone today, featuring Dr. Amy Killen, Dr. Anna Cabeca, and me, as we share our insights on the significance of progesterone for women’s health and the importance of personalized hormone therapy. In this mashup episode, I explore the importance of individualized hormone therapy and the benefits of progesterone, even post-hysterectomy. Dr. Amy Killen explains how progesterone sensitivity affects some women, discusses the importance of laboratory tests when evaluating hair loss, and cautions against popular but ineffective treatments. Dr. Anna Cabeca emphasizes the need to build foundational health before starting bioidentical hormones and outlines her approach to hormone replacement. Join us for an informative discussion on how progesterone, when tailored to individual needs, can support hormone balance and overall well-being. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Amy Killen On her website HopBox (Supplement Company) Subscribe to Dr. Amy’s Substack Connect with Dr. Anna Cabeca Website On social media: @the girlfriend doctor

Today, I am delighted to reconnect with Dr. Roseann, an integrative children's mental health expert and the founder of the Global Institute of Children's Mental Health. Over the last 30 years, Dr. Roseann has helped thousands of children and families overcome the most challenging behavioral and mental health conditions. In our conversation today, we take a deep dive into emotional dysregulation, exploring the biology behind it and the origin of emotional triggers. We discuss parenting and boundaries, the effects of rumination and negative thinking, the value of mindset changes, the role of gut health, vagal tone, and the connection between the gut and brain. Dr. Roseann also walks us through QEEG brain testing, touching on pharmacological options, lifestyle, AI, and tech, and sharing her favorite supplement for mental health.  As always, this discussion with Dr. Roseann is rich and insightful, and I know you will enjoy it as much as I did. IN THIS EPISODE, YOU WILL LEARN: What emotional dysregulation is, and what it takes to break free from emotionally dysregulated patterns  How the brain's perception of safety can either support or block emotional regulation Steps to take if you find yourself in a pattern of dysregulation The importance of teaching children about boundaries How changing your mindset can help you break free from negative thought patterns How subliminal negative messaging from parents trickles down to the children The link between rumination and emotional dysregulation How stress affects gut bacteria and impacts brain function The benefits of QEEG brain mapping AI technologies that can help regulate the nervous system Bio: A mental health trailblazer, media personality, and founder of The Global Institute of Children’s Mental Health and Dr. Roseann, LLC, who is on a mission to change the way we view and treat mental health, showing people it's gonna be ok with science-backed tools that calm the brain. With her trademarked BrainBehaviorResetTM Program, she has helped thousands address the most challenging conditions affecting kids and families today, including PANS/PANDAS, OCD, anxiety, mood/behavior, and ADHD/executive functioning. Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Roseann Capanna-Hodge On her website Podcast: Science Fact Solutions for Dysregulated Kids 

I am honored to reconnect with Dr. Will Cole today! Dr. Cole is a leading functional medicine expert who specializes in clinically investigating underlying factors of chronic disease and customizing a functional medicine approach. He is the author of many books, including the New York Times bestseller Intuitive Fasting and, most recently, Gut Feelings, a book I think everyone will benefit from reading.  Today, Dr. Cole and I delve into the impetus behind his latest book, discussing the toxic food culture, mixed messages, the psychology of food, finding peace with food, and how to reduce our toxic tribalism. We also discuss inflammatory foods and their impact on our gut microbiome, the role of the vagus nerve, how chronic stress is the ultimate junk food for the body, the effects of adverse childhood experiences and trauma, and what shame-flammation is. IN THIS EPISODE YOU WILL LEARN: Dr. Cole discusses his latest book, Gut Feelings The role of mixed messages What is most important in the wellness world? Types of foods that do not serve the best needs of our bodies Is it the grain, or is it what we have done to it? What are we feeding our bodies? How to differentiate between poor vagal tone and dysautonomia Stress and how it impacts our biochemistry How stress is implicated in many health problems Re-negotiating your relationship with life The role of trauma in weight loss How shame can be the basis of many physical and emotional health issues. Bio- Dr. Will Cole: Dr. Will Cole is a leading functional medicine expert who specializes in clinically investigating underlying factors of chronic disease and customizing a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and more. He is the host of The Art of Being Well podcast and author of Ketotarian, The Inflammation Spectrum, New York Times bestseller Intuitive Fasting, and now, Gut Feelings: Healing the Shame-Fueled Relationship Between What You Eat and How You Feel. Connect with Cynthia Thurlow Follow on ⁠Twitter ⁠⁠Instagram ⁠⁠LinkedIn⁠ Check out Cynthia’s ⁠website⁠ Connect with Dr. Will Cole On his ⁠website⁠ ⁠The Art of Being Well Podcast⁠ Get a copy of Dr. Will Cole’s new book, ⁠Gut Feelings⁠ ⁠Ep. 138 – Our Authentic Intuition: What It Can Teach Us About Fasting with Dr. Will Cole