The Curbsiders Internal Medicine Podcast

#288 LIVE! Neutropenic Fever featuring Dr. Susan Seo

Aug 2, 2021
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ANECDOTE

Guest Background And Hobbies

  • Susan Seo is a Carolina transplant working at Memorial Sloan Kettering with interests in antibiotic stewardship and cancer ID care.
  • Outside work she enjoys travel, Netflix foreign shows, and Animal Crossing Pocket Camp on iPhone.
INSIGHT

Definition And Risk Stratification

  • Febrile neutropenia simply requires both fever and neutropenia, usually ANC <0.5 or ANC <1 expected to fall to <0.5 within 48 hours.
  • Use risk stratification (MASCC score) to distinguish low- versus high-risk patients for outpatient care.
ADVICE

When To Manage Outpatient

  • Consider outpatient management for solid-tumor patients with brief, mild neutropenia, good performance status, and intact oral intake.
  • Ensure good home supports, ability to reach ER within 60 minutes, and stable renal/liver function before discharge.
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