The Curbsiders Internal Medicine Podcast

#128 Aspirin Overhyped and Overused

Dec 3, 2018
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ANECDOTE

Parenting Shapes Dr. Pandey

  • Dr. Ambarish Pandey shares that raising his four-year-old daughter takes much of his time outside work.
  • Parenting influences his daily life similarly to following a mentor's guidance in medicine.
INSIGHT

Statins Over Aspirin Now

  • Aspirin's benefit in primary prevention has diminished as event rates drop and statins dominate risk reduction.
  • Bleeding risks from aspirin remain, making statins a safer and more effective choice for primary prevention.
INSIGHT

Risk Scores Overestimate Event Rates

  • Recent aspirin trials show lower actual event rates than predicted by risk scores, indicating populations at lower risk than expected.
  • This discrepancy weakens aspirin's apparent benefit for primary prevention due to lower baseline risk.
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