The Peter Attia Drive

#21 - Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation

12 snips
Oct 16, 2018
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INSIGHT

Lipoprotein Function

  • Lipids are hydrophobic and plasma is water based, so lipids cannot circulate freely.
  • Lipids require water-soluble transportation vehicles called lipoproteins.
INSIGHT

Lipoprotein Structure

  • Lipoproteins are protein-wrapped collections of lipids enabling their circulation in plasma.
  • Albumin, the most frequent protein in blood, carries cholesterol and phospholipids, acting as a carrier.
ANECDOTE

Gofman and Lipoprotein Discovery

  • John Gofman, a physicist, used ultracentrifuges to separate lipoproteins.
  • Dayspring jokes that atherosclerosis is "illegal dumping" of sterols by lipoproteins in arterial walls.
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