

#21 - Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation
12 snips Oct 16, 2018
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Lipoprotein Function
- Lipids are hydrophobic and plasma is water based, so lipids cannot circulate freely.
- Lipids require water-soluble transportation vehicles called lipoproteins.
Lipoprotein Structure
- Lipoproteins are protein-wrapped collections of lipids enabling their circulation in plasma.
- Albumin, the most frequent protein in blood, carries cholesterol and phospholipids, acting as a carrier.
Gofman and Lipoprotein Discovery
- John Gofman, a physicist, used ultracentrifuges to separate lipoproteins.
- Dayspring jokes that atherosclerosis is "illegal dumping" of sterols by lipoproteins in arterial walls.