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Mind & Matter

Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino | 158

May 16, 2024
Researcher Dominic D'Agostino delves into ketosis and the ketogenic diet, discussing their effects on diabetes, brain health, exercise performance, and cancer. They explore metabolic health biomarkers, medication interactions, and the bias towards carbohydrate-centric diets. The conversation also touches on the therapeutic applications of ketosis, including its potential benefits for neuropsychiatric diseases and migraines.
01:41:30

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Quick takeaways

  • Transitioning to whole foods can improve metabolic health.
  • Mainstream dietary guidelines conflict with evidence supporting low-carb diets for insulin resistance.

Deep dives

Growing Research Interest in Ketogenic Diet and Brain Health

Research on ketogenic diets has seen a significant surge, with a focus on its various mechanisms such as reducing oxidative stress, altering neurotransmitter balance, impacting NAD levels, reducing inflammation, and influencing epigenetic signaling. Clinical trials have expanded in areas like cancer cachexia, muscle wasting, and metabolic health. The research landscape is rapidly evolving with nearly 490 clinical trials registered on clinicaltrials.gov, indicating an exponential increase in research interest and potential insights to come.

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