Hacking Your ADHD Research Recap with Skye: Default Mode Network
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Jul 25, 2025 
Skye Waterson, a specialist from Unconventional Organization focused on aiding individuals with ADHD, dives into the intriguing role of the default mode network in ADHD. They explore how this brain network affects attention and task performance, highlighting the intersection of genetics and treatment outcomes. The discussion also sheds light on the potential of Cognitive Behavioral Therapy to alleviate symptoms and improve brain connectivity, plus the unique challenges faced by those diagnosed with ADHD later in life.
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Default Mode Network in ADHD
- The Default Mode Network (DMN) activates during rest and self-reflection, interfering with focus in ADHD brains.
- ADHD brains may fail to deactivate DMN during tasks, causing symptoms like daydreaming and distraction.
Genetics Link to ADHD Brain Function
- Genetic variants may influence brain development and DMN interference, causing cognitive dysfunction and ADHD symptoms.
- This gene-brain-behavior framework links genetics directly to ADHD through brain network alterations.
CBT Alters Brain Connectivity
- CBT showed significant reductions in ADHD symptoms tied to increased brain connectivity between specific regions.
- This demonstrates CBT’s measurable impact on brain plasticity in adults with ADHD.