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Norepinephrine Shortage
- During a norepinephrine shortage, patients with septic shock were switched to phenylephrine.
- This natural experiment revealed increased mortality with phenylephrine, highlighting norepinephrine's importance.
Drug Shortages as Natural Experiments
- Drug shortages, while inconvenient, create valuable natural experiments.
- These events allow for comparisons between treatments as patient conditions are unrelated to shortages.
The President's Lifespan
- A study compared the lifespans of presidents/prime ministers to election runners-up.
- It found that winning the election was associated with decreased life expectancy, suggesting the impact of stress.