The Resus Room

Lactate; Roadside to Resus

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Jul 18, 2022
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INSIGHT

Anaerobic Metabolism

  • Anaerobic metabolism, using glycolysis, produces pyruvate, which is then converted to lactate.
  • This conversion also regenerates NAD, crucial for continued glycolysis and limited ATP production.
INSIGHT

Lactate's Role

  • Lactate, a product of anaerobic metabolism, is vital for energy production when oxygen is limited.
  • It's produced by cells and metabolized by the liver, with some excreted by the kidneys.
INSIGHT

Causes of High Lactate

  • High lactate levels aren't solely due to poor perfusion; various factors contribute.
  • Consider liver disease, accelerated glycolysis, and congenital disorders.
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