

#520 How To Diagnose & Improve Insulin Resistance, The TRUTH About GLP-1 Drugs & More w/ Dr. Rand
May 1, 2025
Dr. Johanan Rand, founder of Healthy Aging Medical Centers, returns to share his insights from over two decades in functional medicine. He dives into overrated and underrated health metrics, offering practical ways to assess insulin resistance at home. Rand sheds light on the implications of GLP-1 drugs, emphasizing a balanced approach of lifestyle changes and medications. He critiques traditional health metrics like BMI and champions markers such as fasting insulin, making a compelling case for personalized and proactive health management.
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Overrated Metrics in Health Checks
- Doctors often rely on limited blood work and BMI, which is outdated and ignores body fat percentage.
- Early signs of insulin resistance can be missed because normal lab ranges are too wide and not optimal.
Target Triglyceride to HDL Ratio
- Aim for triglycerides to HDL ratio below 1, meaning your HDL is higher than triglycerides.
- Higher ratio signals worse insulin resistance and increases risk of metabolic disease.
Simple Insulin Resistance Check
- Measure waist circumference and divide by height; a ratio under 1 shows better insulin sensitivity.
- Hypertension often signals insulin resistance due to endothelial dysfunction and impaired nitric oxide production.