The Optispan Podcast with Matt Kaeberlein Female Biohacker: Why Women Need Different Longevity Protocols (Simple Steps)
Sep 30, 2025
In this enlightening discussion, Kayla Barnes, a longevity clinician and biohacker, shares her journey from a conventional lifestyle to health optimization. She highlights how toxin reduction and consistent practices, like sauna use, can transform health. Kayla explores female-specific longevity issues, emphasizing the impact of ovarian aging and the need for more research. She dives into cutting-edge therapies such as therapeutic plasma exchange and hyperbaric oxygen, revealing their potential benefits while stressing the importance of evidence-based protocols.
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Prioritize Lifestyle First
- Prioritize sleep, exercise, and whole-food nutrition as the foundation of longevity.
- Build VO2 and strength training into routines and track metrics like VO2 and grip strength.
Whole Foods And Balanced Protein
- Eat largely whole foods, avoid ultra-processed products, and emphasize diverse plants and fiber.
- Aim for ~25–35 g fiber daily and moderate protein (Kayla targets 0.6–0.7 g/kg bodyweight now).
Advanced Tools After Basics
- Many advanced therapies add incremental benefit after the basics are optimized.
- Use them to experiment once sleep, exercise, and diet are solidly in place.