The Optispan Podcast with Matt Kaeberlein

The hosts share intriguing takeaways from the LiveLong Conference, diving into topics like Therapeutic Plasma Exchange (TPE) and its potential for enhancing cognitive health. They explore the intersection of brain injuries and psychedelics through the experiences of an NHL player. Navigating health misinformation is a key focus, emphasizing the importance of accurate communication. Discussions on hormone replacement therapy are featured, alongside critiques of prevalent myths in longevity science, urging for clearer discourse in this evolving field.

Matt Kaeberlein shares his insights from a Cleerly CCTA scan, discussing the crucial differences between soft and calcified heart plaque. He delves into the importance of early detection for cardiovascular health and empowers listeners with knowledge on assessing their own risks. The conversation also explores radiation concerns and the actionability of scan results, urging everyone to take charge of their heart health. With practical advice and personal experiences, this discussion highlights the significance of proactive health measures.

Subscribe to our channel: https://www.youtube.com/@optispanGet Our Newsletter (It's Free): https://www.optispan.life/Help Texts CEO Emma Payne discusses the profound impact of grief on health (physical/mental), effective coping strategies (Warden's Tasks), and how text-based support can help navigate loss and foster post-traumatic growth.0:00 Intro: Grief's Impact on Health & Biology1:12 Defining Grief: Lost Connection & Blunt Force Trauma2:55 How Grief Disrupts the Pillars of Health4:12 The Social Isolation of Grief & Why Support Falters12:00 Warden's Tasks of Mourning: A Framework for Coping25:58 Beyond Death: Disenfranchised Grief (Jobs, Pets, etc.)37:01 Post-Traumatic Growth: Finding Strength After Loss43:06 Help Texts Explained: Text-Based Grief Support44:48 The Origin Story of Help Texts1:09:39 How to Effectively Support Someone GrievingProduction: Tara Mei, Nicholas Arapis, https://videocastproductions.comDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!

Explore the fascinating debate on rapamycin as a longevity treatment. Discover how misinformation surrounding its side effects, like cataracts and glucose issues, is debunked with scientific evidence. Uncover the benefits often overlooked in studies, and learn about its potential applications in treating periodontal disease. The discussion dives deep into the biological mechanisms behind mTOR and fasting, while also emphasizing the need for more robust clinical trials. Prepare for a lively examination of truth versus myth in the world of longevity science!

Siim Land, a biohacking expert and author of The Longevity Leap, joins to discuss science-backed strategies for enhancing health span. He delves into the critical distinctions between healthspan and lifespan, emphasizing the importance of quality over mere longevity. The conversation tackles navigating misinformation in the health space, particularly about supplements and lifestyle choices. Siim shares insights from his creatine experiment and highlights essential biomarkers for health monitoring, while advocating for a balanced approach to diet, exercise, and social connections.

Discover a groundbreaking approach to aging that emphasizes health over mere longevity. The discussion dives into Healthspan Medicine, advocating for proactive strategies to enhance well-being as we age. Collaboration among healthcare professionals is key, alongside personalized lifestyle choices and advanced diagnostics. It’s all about living better, not just longer!

Dr. Marcus Ranney, a leading longevity physician from India, and Dr. Brian Kennedy, a biochemistry professor at the National University of Singapore, share insights on advancing longevity science. They discuss India's unique health challenges despite a vegetarian diet and the role of AI in transforming healthcare. Topics include groundbreaking research on stem cell therapy, the importance of hormone replacement, and the effectiveness of supplements like NMN and NAD+. The conversation emphasizes personalized medicine and innovative health monitoring solutions for better aging.

Dr. Christin Glorioso, founder of NeuroAge Therapeutics, dives into the cutting-edge landscape of brain aging and Alzheimer’s prevention. Discover how innovative tests predict Alzheimer’s risk decades ahead, combining genetic insights with lifestyle choices. Glorioso discusses the power of diet, exercise, and sleep on cognitive health, alongside the latest advancements in medications like GLP-1 agonists. Plus, learn about the fascinating role of MRI scans and neural games in assessing brain health, making a compelling case for the future of cognitive well-being.

Dr. Mary Pardee, co-founder and CEO of DeepMind, shares her expertise on gut health and the microbiome. She delves into the complexities of IBS, discussing effective treatment options through diet and lifestyle changes. The conversation debunks myths surrounding microbiome testing and evaluates the reliability of direct-to-consumer tests. Mary emphasizes the importance of probiotics and sheds light on the supplement market, revealing what's genuinely beneficial for gut health. This insightful talk is packed with science-backed tips for long-term wellness!

Dive into the world of biological age tests and discover why many may not be as reliable as claimed. Explore the significant issues surrounding their accuracy and lack of regulatory validation. Learn about the real biomarkers that can enhance longevity and well-being instead of relying on misleading tests. This insightful discussion helps you rethink whether spending money on these tests is truly worthwhile.