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Regenerative Health with Max Gulhane, MD
40. Sarah Kleiner: Leptin Resistance, Circadian Rhythms and Optimsing Hormones with Light
Oct 15, 2023
In this podcast, leading quantum health practitioner Sarah Kleiner discusses the nuances of seasonal eating, the importance of addressing leptin resistance, the effect of circadian disruption on cancer, and optimizing hormone balance through a restorative morning routine and correct signaling through light and food. She also explores the lack of integration of circadian biology in medicine and delves into functional medicine, cellular hydration, and mitochondrial function.
01:20:44
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Quick takeaways
- Maintaining circadian health and optimizing leptin signaling are crucial for overall health and metabolic disease management.
- Cold therapy can improve mitochondrial function and promote fat loss, but it should be approached gradually and with caution, especially for women in different stages of their menstrual cycle.
Deep dives
Importance of Circadian Health and Leptin Signaling
Maintaining circadian health and optimizing leptin signaling are key factors in promoting overall health and addressing metabolic diseases. Leptin, a master circadian signaling hormone, impacts various bodily functions, including thyroid, insulin, and sex hormones. To improve leptin sensitivity, it is crucial to prioritize circadian rhythms by adopting a restorative morning routine, such as wearing blue blockers until sunrise and getting adequate sunlight exposure. Consuming a protein-rich breakfast with some fat helps provide a strong leptin signaling. Fasting can be beneficial but should be approached with caution and only implemented after achieving optimal leptin signaling for at least eight weeks. Women should be mindful of their menstrual cycle and consider following a moon cycle, avoiding fasting during the second half of the cycle. Additionally, cold exposure can enhance mitochondrial efficiency but should be practiced in moderation, around three times per week for three to five minutes, avoiding excessive cold exposure during days 21 to 28 of the menstrual cycle.
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