The Chris and Paul Show
why mTOR is blah and why you don't need to bulk for gains
Nov 23, 2024
Unusual warm weather opens a discussion on climate change, leading to skepticism about the mTOR pathways in muscle growth, branded a 'nothing burger.' The hosts challenge bulking myths, emphasizing smarter dietary and training strategies. They delve into the deceptive nature of social media in fitness portrayals, illustrating the need for skepticism. Individual physiological responses to exercise are crucial, focusing on custom training and understanding muscle fiber types. Finally, they caution against relying on anecdotal evidence, stressing the importance of scientific principles in fitness.
01:04:24
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Quick takeaways
- The mTOR signaling pathway's complexity highlights that muscle protein synthesis requires muscle damage rather than just high signaling levels.
- Training experience significantly impacts muscle protein synthesis rates, revealing that untrained individuals respond differently than those already conditioned.
Deep dives
Understanding mTOR Signaling
The mTOR signaling pathway is a crucial mechanism that facilitates communication from the cell membrane to muscle protein synthesis processes. It acts as a regulator that connects mechanical signals from muscle contraction to the elevation of muscle protein synthesis and myofibrillar protein synthesis. However, the relationship is not straightforward; higher mTOR signaling does not guarantee increased muscle protein synthesis without the presence of muscle damage. This complexity highlights the need for understanding the nuances of muscle adaptation, especially between untrained and trained individuals.
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