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Huberman Lab

Dr. Sean Mackey: Tools to Reduce & Manage Pain

Jan 15, 2024
Guest Dr. Sean Mackey, Chief of Pain Medicine at Stanford University, discusses pain thresholds, effective pain protocols, the influence of emotions on pain perception, the opioid crisis, and the efficacy of cannabis for pain management.
02:52:39

Episode guests

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Quick takeaways

  • Pain perception involves both sensory and emotional components, and the brain actively shapes and interprets pain signals.
  • Rubbing, shaking, and the use of heat and cold can provide effective relief from pain by altering signals in the spinal cord and activating touch fibers that inhibit pain.

Deep dives

The Origins and Nature of Pain

Pain is a complex and subjective experience that serves a crucial role in keeping us away from injury or harm. It involves both sensory and emotional components and is highly individual. Chronic pain is a widespread problem that takes a toll on individuals and society. Understanding the foundations of pain and dispelling misconceptions is essential for effective treatment options.

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