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Immune
Immune 78: Tolerance and tolerating many vaccines
Mar 26, 2024
Exploring hyper vaccination with 217 COVID doses, modifying antigens for immune response suppression, gut bacteria promoting tolerance in neonates, immune responses to SARS-CoV-2 challenge, and ethical concerns in vaccine testing.
01:24:03
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Quick takeaways
- Hyper-vaccination shows robust adaptive immune response but not recommended for immunity enhancement.
- Synthetically glycosylated antigens can suppress established immune responses, offering potential immunomodulation.
Deep dives
Hyper Vaccination Study: Adaptive Immune Response
A study discusses hyper-vaccination in an individual who received COVID-19 vaccines up to 217 times over 29 months. The study found that despite multiple daily vaccinations, the individual maintained a robust adaptive immune response with increased antibodies and T cells. However, the study does not recommend hyper-vaccination as a strategy for enhancing immunity.
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Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode