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Immune Responses and Viral Clearance in SARS-CoV-2 Infection
This chapter delves into a study on immune correlates after SARS-CoV-2 infection challenge in seronegative adults, exploring viral shedding, symptoms correlation, and immune responses in nasal fluid and plasma. It discusses the efficacy of remdesivir treatment, differences in viral replication between the nose and throat, and the role of T cell responses in viral clearance. The chapter emphasizes the importance of CD8 T cells in limiting disease severity and transmission.