Smarter Not Harder Dr. Mariza Snyder on Women's Midlife Metabolism | SNH Podcast #151
Nov 26, 2025
Dr. Mariza Snyder, a naturopathic doctor and women's hormone-health expert, joins the conversation to shed light on perimenopause and midlife metabolism. She describes perimenopause as a 'second puberty' that affects every aspect of women's health. Discover how insulin resistance and hormone balance shape energy and mood, and why sleep is essential during this transition. Dr. Mariza also highlights the significance of testosterone for vitality and recommends practical strategies like movement and community to thrive through midlife.
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Perimenopause As A Second Puberty
- Perimenopause is a 'second puberty' that feels like a hormonal descent reshaping identity and physiology.
- Many women aren't prepared for this multi-year transition and report "I don't feel like myself anymore."
Ovulation Is The Cycle's Main Event
- Ovulation is the "main event" of the cycle and progesterone only rises if ovulation occurs.
- Anovulatory cycles reduce progesterone peaks and disrupt the estradiol-progesterone rhythm that supports whole-body health.
Estrogen Excess And Progesterone Loss
- Erratic or excess estrogen plus poor clearance (liver/gut) produces bloating, fibrocystic breasts, weight gain, and migraines.
- Progesterone loss also removes GABAergic support, worsening irritability and sleep problems.

