Controlling Alzheimer's? It's possible, she says | EP 289.C
Feb 13, 2024
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Dr. Lisa Mosconi discusses actionable steps to diminish dementia risk, the role of genetics and hormones in women's brain health, the impact of diet on menopause and hormonal health, the protective effect of a longer reproductive lifespan, maximizing brain health through diet and exercise, the feasibility of Alzheimer's prevention, and the benefits of olive leaf extract.
Lifestyle modifications and stress reduction are key factors in improving brain health and reducing the risk of Alzheimer's disease.
Genetics play a smaller role in determining Alzheimer's risk compared to lifestyle choices, environmental factors, and overall medical history.
Deep dives
Importance of Understanding Dementia in Women
The XX Brain podcast episode explores the importance of understanding dementia in women, specifically focusing on Alzheimer's disease. The host, Lisa Mosconi, shares her personal motivation behind writing the book 'The XX Brain' and conducting extensive research on women's brain health. She highlights that statistically, women are more affected by Alzheimer's disease, with two-thirds of patients being women. Mosconi emphasizes the need to address the stigma and lack of research surrounding women's brain health. She discusses the impact of hormonal health and the unique role hormones play in protecting against Alzheimer's, particularly estrogen and its significant decline during menopause. Mosconi also emphasizes that while genetics play a role, other factors such as lifestyle, environment, and medical history can also influence brain health and reduce Alzheimer's risk. She advises a focus on lifestyle modifications and stress reduction as key factors in improving brain health.
Understanding Genetic Factors and Brain Health
The podcast episode delves into the role of genetics in brain health and Alzheimer's risk. Lisa Mosconi shares her research findings that only a small percentage of Alzheimer's cases, around 2%, are caused by genetic mutations, debunking the misconception that genetics are the primary determining factor. She explains that while genetics are important, they are not as causative as commonly believed. Mosconi highlights the significance of lifestyle choices, environmental factors, and overall medical history in influencing brain health. She empowers listeners by emphasizing that they have control over their lifestyle and can make choices that positively impact brain health, regardless of their genetic predispositions.
The Impact of Hormonal Health on Women's Brain Health
The podcast episode explores the unique impact of hormonal health on women's brain health. Lisa Mosconi discusses how hormones, specifically estrogens, play a crucial role in protecting against Alzheimer's disease and overall brain aging. She highlights that menopause, marking a decline in estrogen levels, coincides with significant changes in women's brains and increases their risk of developing Alzheimer's plaques. Mosconi emphasizes the importance of understanding these changes and the need for further research to accurately determine the benefits and risks associated with hormonal replacement therapy. She also suggests that hormone levels in the brain should be measured directly to refine the timing and dosage of hormonal therapies.
The Role of Diet, Exercise, and Lifestyle in Brain Health
The podcast episode emphasizes the significant impact of diet, exercise, and lifestyle on brain health, particularly in women. Lisa Mosconi highlights the association between a healthy diet and reduced risk of Alzheimer's disease, recommending the Mediterranean diet for its positive effects on brain health. She specifically mentions the importance of polyunsaturated fatty acids, such as omega-3s, and their potential benefits in reducing Alzheimer's risk. Mosconi emphasizes the need to minimize processed foods and additives in the diet to promote brain health. Additionally, she discusses the critical role of exercise in preventing dementia, citing studies that show a significant reduction in Alzheimer's risk for women with higher levels of fitness. Mosconi encourages women to prioritize regular exercise, even at lower intensity, to support brain health.
Dr. Lisa Mosconi and I share actionable steps YOU can take to help diminish your risk of dementia. PLUS, learn why genetics may not hold the key to a woman's susceptibility to dementia.