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ZOE Science & Nutrition

The surprising truth about histamine intolerance

Feb 15, 2024
Join Dr. Will Bulsiewicz, a board-certified gastroenterologist and bestselling author, as he dives into the perplexities of histamine intolerance. Learn how histamine acts as a vital signaling molecule but can trigger issues for some. Discover the challenges of diagnosing this condition and the dietary restrictions it imposes. Will shares insights on gut health's role, the potential of DAO supplements, and the importance of a diverse, plant-based diet for managing symptoms. Don't miss this essential discussion to understand how to eat smarter!
32:59

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Histamine intolerance occurs when the body has impaired DAO activity or a compromised gut barrier, leading to symptoms such as bloating, headaches, and respiratory issues.
  • To prevent histamine intoxication, it is important to avoid consuming spoiled fish and high-histamine cheeses, and to prioritize eating fresh foods and freezing perishable products to reduce histamine intake.

Deep dives

Histamine Intolerance: Understanding the Basics

Histamine intolerance is a condition characterized by hypersensitivity to histamine, a chemical involved in various bodily functions. While histamine is important for our health, excessive histamine can lead to allergic reactions, scombroid fish poisoning, and histamine intolerance. Histamine intolerance is a chronic condition that occurs when the body has impaired DAO activity or a compromised gut barrier, allowing histamine to enter the bloodstream and trigger symptoms. Common symptoms include bloating, headaches, palpitations, and respiratory issues. Diagnosis is challenging, and elimination diets are commonly used to identify trigger foods. Healing the gut and supplementing with DAO can help manage histamine intolerance.

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