The Dr. Hyman Show How to Catch Alzheimer’s Before It Starts, with Dr. Eric Topol
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Jul 23, 2025 
Join Dr. Eric Topol, a leading cardiologist and geneticist, as he shares transformative insights on preventing Alzheimer’s. He discusses the powerful role of AI diagnostics and genetic risk scoring in early detection. Learn about key biomarkers you should know and the importance of tracking health data. Eric emphasizes proactive lifestyle interventions—like diet and exercise—and how they can bolster your immune system while lowering disease risk. This engaging conversation offers a hopeful roadmap for taking control of your health.
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Alzheimer's Early Biomarker Insight
- P-Tau 217 rises 20 years before mild cognitive impairment, indicating Alzheimer's starts decades prior to symptoms.
- Genetic risk increases odds but doesn't guarantee disease; lifestyle and immune resilience are crucial.
Wellderly Study Surprises
- Dr. Topol's Wellderly study found people in their 90s with no chronic illness had minimal genetic underpinnings for longevity.
- Healthy lifestyle and optimism played bigger roles than genetics in their remarkable health span.
Social Connection Reduces Risk
- Prioritize social connections to reduce risks of neurodegenerative, cardiovascular, and cancer diseases.
- Avoid social isolation as it significantly increases inflammation and disease risk.
