Realfoodology Live Longer: How Mitochondrial Function Reduces Signs of Aging | Timeline Longevity
Nov 25, 2025
Jennifer Scheinman, a registered dietitian and head of nutrition education at Timeline Longevity, dives into the fascinating world of mitochondrial health. She explains urolithin A, a post-biotic that supports longevity and is crucial for energy production. Listeners learn how mitochondrial function impacts aging and the surprising ways urolithin A can benefit skin and muscle health. Jennifer also discusses practical lifestyle changes to boost mitochondrial performance and the latest research on immunity and brain health connected to urolithin A.
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Urolithin A Is A Gut-Made Postbiotic
- Urolithin A is a postbiotic produced when gut bacteria convert polyphenols from foods like pomegranates, berries, and nuts.
- Many people lack the specific gut microbes to make urolithin A, so eating pomegranate may not yield it for everyone.
Mitochondria Are Dynamic Aging Drivers
- Mitochondria are abundant and dynamic organelles that fuse, divide, and renew to meet cellular energy demands.
- Their decline is a core hallmark of aging, affecting brain, muscle, skin, and reproductive tissues.
Start With Diet, Sleep, Exercise First
- Protect mitochondria with foundational habits: a nutrient-dense, anti-inflammatory diet, regular exercise, and good sleep/circadian rhythm.
- Add interventions like fasting, red light, cold plunge, sauna, or targeted supplements to boost mitochondrial health.