The Jesse Chappus Show 683: Fewer Calories Won't Make You Lose Weight — This Does... | Dr. Jason Fung
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Dec 16, 2025 
Dr. Jason Fung, a physician and nephrologist renowned for his work on metabolic health and obesity, dives into the fascinating role of hunger hormones in weight loss. He explains why understanding hunger is more vital than counting calories, highlighting the importance of protein, fiber, and food volume. Fung discusses natural satiety aids like bone broth and the appetite-suppressing effects of green tea and coffee. He also shares insights on food processing, the impact of meal order, and the benefits of fasting and ketosis in regulating hunger.
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Body Fat Is A Hormonal Thermostat
- Body fat is regulated like a thermostat driven by hormones, not by simple calorie math.
- When weight changes, hunger adapts to restore the set point through hormonal signals.
Calories Differ By Hormonal Effect
- Not all calories act the same because macronutrient type and food form change hunger and satiety signaling.
- Liquid or refined calories often fail to trigger satiety hormones compared with solid protein/fiber meals.
Choose Foods That Maximize Satiety
- Prioritize high-protein, high-fiber, whole foods to naturally raise satiety hormones like GLP-1 and peptide YY.
- Cut ultra-processed foods because they minimize satiety and promote overeating.