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Non-alcoholic fatty liver disease (NAFLD) is reversible through diet changes and lifestyle modifications. The majority of NAFLD cases are a result of lifestyle factors, particularly changes in diet and the increased consumption of ultra-processed foods. Genetics play a minor role in hereditary cases. Insulin resistance is the underlying cause of many chronic diseases, including NAFLD and cancer. Radiologists are observing a rising prevalence of cancers and NAFLD in younger populations due to metabolic dysfunction. A simple three-step plan emphasizes avoiding processed seed and vegetable oils, adopting a low-carb and low-sugar diet, and practicing intermittent fasting. This three-step plan can also help prevent other chronic diseases, such as heart disease and type 2 diabetes.