
High Performance Health Beyond the Scale: Why Muscle Is the Key to Longevity with Dr Gabrielle Lyon
Nov 24, 2025
Dr. Gabrielle Lyon, a physician and researcher specializing in muscle health, joins the discussion on the importance of skeletal muscle for longevity and metabolic stability. She reveals that muscle, not fat, is crucial for healthy aging, particularly for women in perimenopause. Lyon challenges traditional protein recommendations, advocating for increased intake and resistance training to combat muscle loss. The conversation also addresses metabolic health, the pitfalls of fasted training, and how building physical strength enhances mental resilience.
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Muscle As The Central Organ For Health
- Skeletal muscle is essential for health and longevity and must be prioritized over focusing solely on body fat.
- Dr. Gabrielle Lyon states there is no way to be healthy without skeletal muscle mass.
Daily Protein Target For Muscle
- Aim for roughly one gram of protein per pound of ideal body weight daily to support muscle and repair.
- Increasing protein above standard RDA has no harmful effects for healthy people and supports better body composition.
Protect Muscle During Perimenopause
- Perimenopause accelerates muscle loss and shifts fat centrally, so increase protein intake and resistance training.
- Combine dietary protein, effective training, and consider hormonal therapy if clinically appropriate to prevent sarcopenic obesity.




