Moonshots with Peter Diamandis

David Sinclair (Harvard Professor) Reveals Age-Reversing Science to Look & Feel Younger

250 snips
Jun 26, 2025
In this enlightening discussion, David Sinclair, a Harvard genetics professor and biotech entrepreneur, reveals groundbreaking insights into anti-aging science. He explores revolutionary breakthroughs in gene therapy and the role of AI in making age reversal accessible. Sinclair discusses the potential of epigenetic reprogramming to rejuvenate cells and shares exciting advancements in regenerative medicine. He advocates for community support in longevity research to overcome funding challenges, emphasizing the future of health and wellness.
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INSIGHT

Epigenetic Reprogramming Reverses Aging

  • Aging can be reversed by resetting the epigenome using gene therapy to turn on embryonic genes in adult tissues.
  • This approach has cured diseases in mice and monkeys, including blindness, showing potential for human applications.
INSIGHT

Aging as Epigenetic Software Corruption

  • Aging results from loss of cellular information in the epigenome, akin to software corruption in a computer.
  • The epigenome can be safely reset without cloning, effectively rebooting cells to a youthful state.
ADVICE

Exercise Maintains Longevity

  • Prioritize weightlifting or resistance exercise especially after age 50 to maintain muscle mass and mobility.
  • Avoid prolonged sitting and incorporate movement throughout the day for longevity benefits.
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