BV #5: Robert Lustig on Fructose, Dave Asprey’s Criticism of Ray Peat, & Jordan Peterson on Serotonin

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Dec 19, 2024

In this conversation, Jack, co-creator of Analyze & Optimize, shares insights into Ray Peat's dietary principles and critiques Robert Lustig's claims about fructose being as harmful as alcohol. The discussion also touches on the complex role of serotonin, challenging its portrayal as simply a 'happy hormone,' and dives into the potential negative impacts of the carnivore diet on gut health. Additionally, they explore the health risks associated with hormonal contraceptives and reflect on Dave Asprey's views regarding dietary choices.

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ANECDOTE

Analyze & Optimize's Journey to Ray Peat

Analyze and Optimize's YouTube channel initially focused on keto, fasting, and carnivore diets.
Their shift towards Ray Peat's work began after exploring it in late 2020, leading to content debunking popular dietary narratives.

INSIGHT

Fructose Metabolism vs. Alcohol

Robert Lustig's claim of a 25-gram fructose limit is likely based on epidemiological studies, not direct physiological evidence.
Fructose metabolism, involving two enzymatic steps before entering glucose pathways, differs significantly from alcohol.

INSIGHT

Fructose Absorption and Gut Health

Studies using high fructose doses often involve isolated fructose, which is poorly absorbed and causes gut issues, not metabolic problems.
Co-administering glucose with fructose drastically improves absorption, suggesting gut health, not fructose itself, is the primary concern.

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In this episode we discuss:

How Jack & Dalton from Analyze & Optimize were introduced to the work of RayPeat
Robert Lustig's claims that fructose is as harmful to the liver as alcohol
Whether Jordan Peterson’s Serotonin Hierarchy has any merit
The negative effects of the carnivore diet, especially on gut health
The link between birth control and cancer and the protective effects of progesterone
What we think of Dave Asprey’s thoughts on the “Ray Peat diet”

Analyze & Optimize's Website: https://www.analyzeandoptimize.io/

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Danny's Telegram: https://t.me/dannyroddy

Timestamps:

0:00 – intro

0:38 – how Analyze & Optimize (Jack & Dalton) got introduced to work of Ray Peat

6:32 – how Analyze & Optimize create their videos

10:40 – refuting Robert Lustig's claims – is fructose as harmful to the liver as alcohol?

17:40 – whether Analyze & Optimize are paid by “big sugar”

20:30 – Robert Lustig’s fructose claims are unsupported

28:06 – is white sugar safe to consume?

33:04 – Serotonin & Hierarchy by Jordan Peterson

34:33 – SSRI use and serotonin’s role in promoting learned helplessness and anhedonia

40:46 – how the perceived benefits of serotonin could be attributed to other factors

45:45 – whether serotonin is the “dominance” hormone

47:17 – Analyze & Optimize respond to Shawn Baker on sugar cravings being a sign of health and youth

51:04 – declining health on the carnivore diet, whether it’s sustainable, and why your immune system needs carbohydrates

54:04 – carnivore diet effects on gut health – quorum sensing, biofilms, high stress hormones, and damage to thyroid health

1:01:30 – why chronic low-calorie intake turns down metabolic function and leads to obesity

1:07:00 – the harm caused by conflating progesterone and synthetic progestins

1:14:57 – the link between birth control and cancer and the protective effects of progesterone

1:18:20 – the negative effects of synthetic progestins and estrogen, especially unchecked by natural progesterone

1:24:45 – Why Is the Right So Obsessed with Seed Oils? by Ej Dickson

1:31:15 – Dave Asprey argues with Paul Saladino on supplements vs orange juice

1:39:10 – whether Ray Peat’s ideas and principles promote orthorexia

1:44:22 – using precision medicine vs. listening to your body

1:51:09 – where to find more of Jack & Dalton’s work