Understanding CNS Fatigue versus Peripheral Fatigue

CNS fatigue involves a reduction in muscle force output due to diminished nervous system signals, while peripheral fatigue is linked to muscular factors like energy depletion and metabolic byproducts. Central fatigue can persist longer than peripheral fatigue, maintaining its effects for several days as opposed to the hours typically seen with peripheral fatigue. This distinction is crucial for athletes, as it emphasizes the importance of understanding how central nervous system output can affect performance. Physiologically, factors like neurotransmitter depletion, altered motor neuron excitability, and protective sensory feedback mechanisms contribute to CNS fatigue.