

Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Dr Amy Kaji
Feb 6, 2020
Dr. Amy Kaji, an MD, PhD specializing in Noninferiority Trials, discusses concepts such as minimal clinically important difference, one-way vs two-way statistical tests, and the differences between noninferiority and superiority trials. The importance of selecting the minimally important clinical difference and sample size for trials is also emphasized.
Chapters
Transcript
Episode notes
1 2 3 4 5
Introduction
00:00 • 2min
Understanding the Role of Minimal Clinically Important Difference in Non-inferiority Analysis
01:49 • 3min
Distinguishing One-Way and Two-Way Statistical Tests in Noninferiority Trials
04:58 • 2min
Differences between noninferiority and superiority trials
07:18 • 2min
Selecting the Minimally Important Clinical Difference and Sample Size for Trials
09:02 • 2min