
Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Dr Amy Kaji
JAMAevidence JAMA Guide to Statistics and Methods
Understanding the Role of Minimal Clinically Important Difference in Non-inferiority Analysis
This chapter explores how the concept of minimal clinically important difference affects non-inferiority analysis in clinical trials, discussing factors considered in determining this difference and its impact on statistical design and sample size.
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