The Neuro Experience

#347: Why Nitric Oxide is the Key to Heart and Brain Health | Dr. Nathan Bryan

42 snips
Jun 20, 2024
Guest
Nathan Bryan
Dr. Nathan Bryan discusses nitric oxide's role in heart and brain health, highlighting its decline with age and the link to diet. He explores the surprising connection between oral hygiene and nitric oxide levels. Topics include nutrient depletion in the standard diet, nitric oxide in mitochondrial function, and controversies surrounding nitrates in food.
Ask episode
AI Snips
Chapters
Transcript
Episode notes
INSIGHT

Nitric Oxide Is A Fleeting Master Regulator

  • Nitric oxide is a short-lived gaseous signaling molecule that controls vasodilation, neurotransmission, and immune killing of pathogens.
  • Its half-life is under a second, so production must occur continuously to regulate blood flow and organ function.
INSIGHT

Age-Related Loss Drives Systemic Disease

  • Nitric oxide production declines with age and this loss links to many chronic diseases like hypertension, ED, and dementia.
  • Restoring nitric oxide production can prevent or reverse age-related organ dysfunction driven by poor perfusion.
INSIGHT

NOS Must Stay 'Coupled' To Make NO

  • NOS enzyme converts L-arginine to nitric oxide but requires cofactors like BH4; when BH4 oxidizes, NOS
Get the Snipd Podcast app to discover more snips from this episode
Get the app