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The Intern At Work: Internal Medicine
116. Body on Fire - Approach to Hyperthyroidism
Nov 28, 2021
17:24
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- Management of hyperthyroidism involves anti-thyroid drugs, radioactive iodine therapy, or surgical interventions.
- Diagnosing thyroid storm requires clinical criteria like thermoregulatory dysfunction and arrhythmias, along with assessing hormone levels.
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Understanding Thyroid Physiology and Hormonal Regulation
The thyroid gland functions as a key part of the signaling cascade involving the hypothalamus and anterior pituitary gland to regulate thyroid hormone levels. Thyroxine (T4) and triiodothyronine (T3) are crucial thyroid hormones that modulate metabolic rates, cardiac output, bone reabsorption, and sympathetic nervous system activity. Feedback mechanisms ensure proper hormone levels, yet dysregulation can lead to hyperthyroidism, characterized by excess thyroid hormone production due to factors like Graves' disease or thyroid masses.
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