Iron Culture presented by MASS Ep. 89 - Supplement Science: What You DON’T Know About Caffeine & Stimulants
Oct 19, 2020
In this episode, the guest discusses caffeine, covering its pharmacokinetics, mechanisms of action, performance-enhancing effects, side effects, withdrawal, dependence, and other nutraceuticals that can modify its effects. They also explore the social acceptability of caffeine, the field of pharmacology, and the individualized use of caffeine in training sessions. Additionally, they highlight the importance of being an informed consumer of supplements and provide useful websites for analyzing ingredients and understanding their effects.
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Pharmacology Basics for Supplements
- Pharmacology explains how drugs influence physiology, including absorption, distribution, metabolism, and excretion.
- Nutrients and supplements also follow pharmacological principles affecting their efficacy and interaction in the body.
Caffeine Absorption Dynamics
- Caffeine is almost 100% absorbed in the gastrointestinal tract, reaching peak blood levels about 45 minutes after ingestion.
- Fat consumption can delay caffeine absorption, affecting the timing of its effects.
Factors Affecting Caffeine Metabolism
- Genetic and lifestyle factors like smoking and estrogen levels influence how quickly caffeine is metabolized.
- Caffeine's half-life averages five hours, affecting how long its stimulatory effects persist and impact sleep.