The Curious Clinicians

68 - A Fib About PE

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Apr 5, 2023
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INSIGHT

Reverse Relationship between AFib and PE

  • Atrial fibrillation (AFib) is commonly understood as a consequence of pulmonary embolism (PE).
  • However, the reverse relationship, where AFib might be a risk factor for PE, is less explored.
INSIGHT

AFib and VTE Risk

  • Studies show a higher incidence of venous thromboembolism (VTE), particularly PE, in patients with new-onset AFib.
  • This risk is most pronounced within the first 30 days of AFib diagnosis, with hazard ratios ranging from 2.2 to 11.8 across studies.
INSIGHT

Right Atrial Thrombus Formation

  • Autopsy and echo studies reveal the right atrium as a site of thrombus formation in AFib patients.
  • This challenges the assumption that deep vein thrombosis (DVT) is the sole source of PE, as only 50% of PE patients present with DVT.
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