The Peter Attia Drive

#05 - Dom D’Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer

Jul 16, 2018

02:43:06

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Episode guests

Dom D’Agostino

Highlights

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Episode notes

Glutamine, Glutaminolysis, Metformin & Aspartate in Cancer

03:18

Targeting the Hallmarks of Cancer with Ketogenic Diet

01:00

Predictable Decrease in Blood Glucose with Ketone Esters

01:01

Interpreting Urinary Ketone Test Results

01:51

Introduction

5min

I'm Doing Really Well. And I've Got a Question for You, Ken Ford. And So That Was the Night We Met

2min

Postdoctoral Fellowship in Neuroscience

2min

The Hyperbaric Atomic Force Microscope

2min

Using a Confoca Microscope to Image Cancer Cells

3min

Observation Two, Lots of Mitochondria in Cancer Cells

4min

Cancer Cells

3min

Cancer Cells Are Not Growing as Rapidly as They Should Be

6min

Is the Warburg Effect Presenta Present?

2min

10.

The Warburg Effect on Cancer Cells

2min

11.

Cancer Metabolism Conferences - Is There Another Reason Why?

2min

12.

Cancer

2min

13.

The Problem of Oxygen Toxicity Seizures

3min

14.

Do You Know How Many Navy Divers Die From Seizures?

3min

15.

The Adaptive Response to Oxydative Stress

3min

16.

Hyperbaric Medicine

2min

17.

Hyperbaric Oxen Therapy for Trematic Brain Injury

2min

18.

Tbi

2min

19.

Hyperbaric Auction Therapy

2min

20.

Did George Khill Do the Exogenous Keytones?

2min

21.

The Metabolic Effect of Beta Hydrox Buterate

2min

22.

Is It a Triglyceride, or a Fatal Fatty Acid?

1min

23.

Ylie Hant, You Theo Mice?

2min

24.

How Much of Your Brain's Energy Comes From Glucose?

2min

25.

What Are Key Tones and How Do They Change Your Metabolic Physiology?

2min

26.

Ketogenic Diet - Key Tone Esters

3min

27.

How to Make a Keytone Body?

3min

28.

Is Aspertate Associated With Cancer Cells?

3min

29.

Pritin, Medium Chain Triglyceride, and Metabolic Fats

2min

30.

C a Oil

2min

31.

Powdered Mc Ts

2min

32.

Do M C Ts Cross the Blood Brain Barrier?

2min

33.

The Anti Seizure Properties of Aketogenic Diet

2min

34.

Can Exogenous Keytones Work for Seizures?

3min

35.

The Keytones Are Driving Down Glucose Levels

4min

36.

How Do We Measure Insolent Wasles?

2min

37.

Is Your Urine Meter a Good One?

3min

38.

Nemo 23: What Did You See That You Did Not Expect?

2min

39.

Do You Think Temperature and Pressure Are the Differences?

3min

40.

Then, Is It a Topagy Sky Rocket?

2min

41.

Is That Vitali One Keytone?

2min

42.

Is There a Triuster of Glyceral?

2min

43.

The Keytone Salts Aren't Bad, but They're Good

2min

44.

Is the Bata Hydroxy Buterate an Antimer?

2min

45.

Do You Have an Anti Seizure Effect?

2min

46.

Organic Chemistry

2min

47.

The Best With Patrick - I Owe a Lot to Patrick

3min

48.

Do Keytone Salts Have More Physiologic Benefits Than Keytones?

2min

49.

Keytone Tolerance Test

2min

50.

The Keyto Jenk Diet

2min

51.

Is There an Upregulation of MCT in Athletes?

2min

52.

G B M Versus Metostatic Bress Cancer?

5min

53.

Is There a Reason Why You Shouldn't Consume Exogenous Ketones During the Fasting Period?

3min

54.

Metabolism Is a Driver for Epigenetic Expression

3min

55.

Reverse Tumor Hypoia Damages

4min

56.

Do Anti Oxidents Really Work?

3min

57.

Epilepsy and D Glucose

4min

58.

Is Hyperbaric Oxygen Therapy a Good Therapy?

4min

59.

Glucos Transporter Type One Deficiency - What's the Longest Fast You've Ever Doe?

4min

60.

Keytone as an Alternative Energy Source

4min

61.

The Metabolic Health Summit

4min

62.

I Want to Thank You and Thank You for Sharing Your Knowledge

3min

Dom digs deep into the research and application of ketogenic diets, exogenous ketones, hyperbaric oxygen treatment, and treating cancer with a metabolic approach. Plus, we lost track of the number of n=Dom experiments mentioned in this episode.

We discuss:

Dom’s early medical training in hyperbaric chambers [7:00];
Effect of ketones on cancer cells [20:00];
Ketones and oxygen toxicity seizures [32:00];
HBOT & its many applications [40:00];
Ketones, MCTs, and exogenous ketones [59:15];
How ketones affect blood glucose [1:20:00];
Ketone esters, salts, enantiomers vs. racemic BOHB [1:38:00];
Dom’s ketone tolerance test [1:56:00];
The metabolic management of cancer with a Press-Pulse approach [1:59:45]; and
More.

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