Core IM | Internal Medicine Podcast

Hepatic Encephalopathy: 5 Pearls Edition Ep3

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Dec 13, 2017
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ADVICE

Differential Diagnosis for Altered Mental Status in Cirrhotics

  • Consider various diagnoses when a cirrhotic patient presents with altered mental status, not just hepatic encephalopathy (HE).
  • Rule out life-threatening conditions like brain bleeds, Wernicke's encephalopathy, and infections.
ADVICE

Precipitants of Hepatic Encephalopathy

  • When diagnosing HE, first ensure medication adherence.
  • Then, consider infections, increased ammonia/azotemia, decreased ammonia clearance, or electrolyte imbalances.
INSIGHT

Asterixis: More Than a Tremor

  • Asterixis, often associated with HE, is a negative myoclonus (lapse in muscle contraction), not a tremor.
  • It indicates dysfunction in brain areas controlling posture (thalamus, basal ganglia) and can be present in other encephalopathies.
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