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The Doctor's Kitchen Podcast

#245 Ozempic. The truth about the side effects and risks of this Magic Pill with Johann Hari

May 1, 2024
Author Johann Hari discusses his weight loss journey with Ozempic, revealing its effects on the brain and gut, addiction to food, and potential risks like cancer. They delve into the history of weight loss drugs, impact on obesity, addiction reduction, and Japan's low obesity rates due to dietary differences.
01:25:57

Episode guests

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Quick takeaways

  • GLP-1 agonists could reduce addictive behaviors like alcohol and substance abuse.
  • GLP-1 agonists have a rare but serious risk of pancreatitis and common side effects like nausea and constipation.

Deep dives

The Effects of GLP-1 Agonists on Addiction Behaviors

Research on rats and mice showed that GLP-1 agonists significantly reduced alcohol, fentanyl, heroin, and cocaine use by 50%, suggesting a potential impact on addictive behaviors. Anecdotal reports from individuals also indicated a reduction in compulsive behaviors like excessive spending. While conclusive human studies are still limited, early findings point to the drugs potentially enhancing self-control and reducing addictive tendencies.

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