The Dylan Gemelli Podcast Episode #42 Featuring Dr. Elizabeth Yurth Part 2! The TRUTH about the NAD craze, Jardiance and SGLT2 inhibitors, AMPK vs mTOR, CLEERLY and other heart scans, TOP FIVE essential supplements, Amino Acid supplements and more!!
Aug 7, 2025
Dr. Elizabeth Yurth, a physician at Boulder Longevity Institute, dives deep into health optimization. She debunks misconceptions about NAD supplementation and discusses its implications for aging. The conversation covers SGLT2 inhibitors and their benefits for heart health and diabetes. Dr. Yurth explains the crucial balance between AMPK and mTOR pathways for longevity. She also critiques amino acid supplements, advocating for whole proteins. With insights on heart scans, she emphasizes the importance of accurate imaging for cardiovascular health.
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Trusted Mentor And Deep Learner
- Dylan Gemelli calls Dr. Elizabeth Yurth one of his go-to resources and mentors.
- Dylan credits her teaching for pushing him from bro-science to deep clinical knowledge.
NAD Decline Is Not The Root Problem
- Elizabeth Yurth explains NAD decline is a symptom, not the primary cause of aging-related dysfunction.
- She identifies CD38 and NNMT as enzymes that drain NAD and drive disease processes.
Avoid Continuous NAD Supplementation
- Elizabeth Yurth warns against regular high-dose NAD/NMN/NR use because senescent and cancer cells exploit added NAD.
- Use precursors sparingly and prioritize blocking NAD-draining enzymes instead.