Matt Walker, a renowned Professor of Neuroscience and Psychology at UC Berkeley, dives deep into the intricate world of sleep. He explores the impact of caffeine on sleep quality, emphasizing genetic differences that affect metabolism. Walker also reviews the effectiveness of sleep trackers, and discusses the pros and cons of substances like THC and CBD. Additionally, he reveals how body temperature influences sleep and innovates with technology like smart mattresses to enhance rest. The conversation uncovers the fascinating interplay between science and sleep optimization.