Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast Episode 24: The Evils of Sodium Bicarbonate
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Dec 11, 2016 AI Snips
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Vasopressin Effective in Vasoplegic Shock
- The VANCS study shows vasopressin up to 0.06 units/min effectively treats vasoplegic shock after cardiac surgery.
- Vasopressin reduced kidney injury, dialysis need, atrial fibrillation, ICU and hospital stays without increasing adverse events.
Low pH Might Not Be Harmful
- Low blood pH may not cause intracellular or mitochondrial acidosis.
- Acidosis can be protective in some cells and may not increase arrhythmias or pulmonary pressures.
Bicarb Raises Blood but Not Cellular pH
- Sodium bicarbonate raises blood pH but worsens intracellular acidosis due to CO2 diffusion.
- It does not improve vasopressor response, cardiac output, or pulmonary pressures in acidotic patients.