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Well with Arielle Lorre

337: The Evolution of “Keto,” & How Ketones Fight Inflammation & Disease with Dr. Michael Wool

Jul 31, 2024
Dr. Michael Wool, a seasoned internist and researcher, discusses the fascinating role of ketones in fighting inflammation and various diseases. He sheds light on the evolution of the ketogenic diet, tracing its journey from epilepsy treatment to a cultural phenomenon. The conversation delves into the science behind sugar-driven systems versus ketosis, and the cellular mechanisms of obesity. Dr. Wool also addresses the therapeutic potential of ketones for brain health, highlighting their advantages in energy production and cognitive support.
50:15

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Understanding ketosis reveals its potential in enhancing metabolic function and reducing inflammation for improved health outcomes.
  • Exogenous ketones provide a rapid alternative to achieve elevated blood ketone levels, offering therapeutic benefits for obesity and neurodegenerative disorders.

Deep dives

Understanding Ketosis and Its Benefits

Ketosis is a metabolic state where the body primarily uses ketones for energy instead of glucose. This process occurs during fasting or a low-carbohydrate diet, leading to various health benefits. It has been shown to help with weight management, reduce inflammation, and improve mental clarity and cognitive function. A key aspect of ketosis is its role as a signaling molecule, which can help regulate cellular interactions, enhancing overall health.

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