The Curbsiders Internal Medicine Podcast

#167 LIVE! Common CBC Abnormalities with Mary Kwok MD

Aug 19, 2019
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ADVICE

Use Absolute Counts in CBC

  • Always calculate and interpret absolute counts in the CBC rather than relying solely on differential percentages.
  • Focus on the absolute neutrophil count, lymphocyte count, and basophilia as key indicators in the differential diagnosis.
ADVICE

Repeat Abnormal CBCs First

  • Repeat abnormal CBC results before pursuing further workup to confirm persistence.
  • In asymptomatic patients with mild abnormalities, advise smoking cessation and then reassess.
ADVICE

Physical Exam for Leukocytosis

  • Always perform a thorough spleen and lymph node exam when evaluating leukocytosis.
  • Check for signs of infection or lymphadenopathy to guide next steps.
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