
LEVELS – A Whole New Level #284 - Glucose metabolism explained: HbA1c, insulin resistance, and strategies for better energy | Dr. Ben Bikman & Mike Haney
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Oct 23, 2025 Dr. Ben Bikman, a metabolic scientist and author, joins Mike Haney to delve into glucose metabolism and insulin resistance. They explore how insulin plays a crucial role in energy regulation and why understanding HbA1c is essential. Dr. Bikman discusses early signs of insulin resistance and practical lifestyle strategies to lower insulin levels naturally. He emphasizes that chronic high insulin can lead to weight gain and fatigue, and highlights the protective role of muscle tissue against metabolic dysfunction.
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How A Fat-Cell Revelation Shaped His Career
- Ben Bikman describes discovering adipose as an active endocrine organ during his studies and how that shifted his research focus.
- That revelation led him to study insulin resistance as the mediator between obesity and type 2 diabetes.
Insulin Resistance Requires High Insulin
- Insulin resistance always coexists with chronically elevated insulin (hyperinsulinemia).
- You cannot accurately describe insulin resistance without accounting for elevated insulin levels systemically.
Three Fast Triggers Of Insulin Resistance
- Three primary, fast causes of insulin resistance are chronic insulin, stress (cortisol/epinephrine), and inflammation.
- Each can induce insulin resistance within hours and may reverse when the stimulus ends.




