The Human Upgrade with Dave Asprey

All the Ways Inflammation and DNA Affect Cardiovascular Health – Mansoor Mohammed, Ph.D. with Dave Asprey : 742

Sep 22, 2020
Mansoor Mohammed, Ph.D., is a medical genomics pioneer and the chief scientific officer at The DNA Company. In this engaging discussion, he reveals how cardiovascular disease often begins with the blood vessel lining rather than the heart. The conversation dives into how inflammation, influenced by genetics and diet, plays a crucial role in cardiovascular health. Mansoor also highlights the significance of understanding genetic predispositions and lifestyle choices in combating inflammation and promoting heart health.
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INSIGHT

CVD Triangle

  • Cardiovascular disease often begins with inflammation in blood vessel linings, not the heart itself.
  • This inflammation is influenced by what's in your blood, the lining's resilience, and your body's inflammation control.
INSIGHT

9P21 Markers

  • The 9P21 genetic markers indicate the resilience of your endothelial glycocalyx (blood vessel lining).
  • More G alleles at these markers correlate with a weaker lining, increasing cardiovascular risk.
ANECDOTE

Dave's 6G Genotype

  • Dave Asprey reveals he has the least favorable 9P21 genotype (6Gs), increasing his susceptibility to inflammation.
  • This genotype also affects nerve lining resilience, making him more vulnerable to Lyme and mold.
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