Discussion of research study on factors contributing to long and healthy life. Insights from study on biomarkers and longevity. Relationship between blood biomarkers, lifestyle factors, and impact of protein intake on lifespan among older adults.
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Quick takeaways
Maintaining lower levels of glucose, creatinine, and uric acid from the 60s onwards contributes to longevity.
High protein intake, especially from fish, is associated with a significant reduction in mortality risk among older adults.
Deep dives
Biomarker profiles of centenarians
A long-term study conducted by the Karolinska Institute in Sweden revealed common biomarkers in people who live past the age of 90 and 100. The study tracked 44,000 Swedes for 35 years, and found that those who lived to be centenarians tended to have lower levels of glucose, creatinine, and uric acid from their 60s onwards. Furthermore, centenarians generally had biomarker values within the reference range, with very few exhibiting extremely high or low levels. The study also found that individuals with the lowest uric acid levels had a 4% chance of reaching 100, while those with the highest uric acid levels had only a 1.5% chance.
High protein intake and lifespan
Another study focused on protein intake and lifespan among older adults. The research, conducted with 833 older adults aged 85 to 89, found that high protein intake was associated with a lower risk of death from all causes. Participants with high protein intakes above 19.1% of energy had a 56% reduced risk of all-cause mortality compared to those with low protein intakes. Additionally, the study highlighted that fish protein intake showed the most significant reduction in mortality risk, with a 50-52% decrease. These findings emphasize the importance of protein intake, particularly from sources like fish, for promoting longevity and overall health.