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Deep sleep is crucial for daily rejuvenation, repair, adequate metabolism, and overall energy levels. Magnesium deficiency, affecting over 80% of the population, can lead to inadequate deep sleep. Magnesium plays a key role in promoting relaxation and aiding sleep, helping individuals awaken feeling refreshed and reducing the risk of premature aging.
Chris Mirabile, the CEO of Nova Slabs, discusses the intersection of health, performance, and longevity. Nova Slabs is dedicated to addressing the nine hallmarks of aging to enhance health span and longevity. By incorporating scientific and medical expertise, they aim to optimize biological health and age to achieve a comprehensive approach to anti-aging strategies.
Short-term health strategies, while beneficial for immediate performance or health outcomes, may not always align with long-term longevity goals. Examples like overuse of antibiotics or high UV exposure demonstrate how prioritizing immediate results can impact overall health span. Striking a balance between short-term gains and long-term health benefits is essential for optimizing overall well-being and longevity.
Addressing cellular senescence through synolytics and nutraceuticals presents a nuanced approach to aging. Ficetin, included in formulations like Novos, exhibits senostatic effects, halting the growth of senescent cells without completely destroying them. This method provides a safer alternative, reducing the risk of cellular toxicity while promoting healthy aging. Individual circumstances and risk tolerance play crucial roles in determining the appropriate usage of senolytics and nutraceuticals for optimal health outcomes.
Starting in the late 20s to early 30s is the optimal time to focus on health as the chances of developing chronic illnesses increase significantly at this age range. By being proactive and addressing health concerns before they manifest, individuals can potentially improve their overall well-being and longevity.
Measuring biological age through advanced tests like epigenomics can provide valuable insights into the rate of aging. Different generations of tests assess not only chronological age but also mortality and disease risk. The Dunedin pace clock is highlighted as a precise measure of aging pace, offering more accurate results than traditional biological age clocks.
If there is one thing that humanity has been striving for since its inception, is the pursuit of longevity. Today I’m with Chris Mirabile, Founder & CEO of NOVOS Labs who brings us one step closer to cracking the code of aging and longevity and offers fascinating insight into the intersection of health, performance, and longevity. We discuss how short-term health strategies may not always contribute positively to longevity, and the nine hallmarks of aging that NOVOS Labs aims to address. These include loss of proteostasis, DNA damage, attrition of telomeres, mitochondrial dysfunction, cellular senescence, altered cellular communication, dysregulated nutrient sensing, epigenetic alterations, and telomere shortening.
Chris’s interest in health began when he was 12 and evolved into a passion after he was cured of a brain tumor when he was 16. Chris has researched and integrated longevity practices and interventions into his life for more than ten years, has achieved a biological age 13.6 years younger than his chronological age, and according to epigenetic tests like DunedInPACE, is aging 31% slower biologically than chronologically. As we dive deeper into the realm of aging and anti-aging strategies, we bring ourselves one step closer to a future where longevity is not just a dream, but a reality.
Chris Mirabile graduated from NYU Stern School of Business and later won their business plan competition with his startup company, Hotlist, a location-based social network that scaled to 220 million people’s social plans. Chris has launched multiple successful technology ventures and has advised biotech startups and NYU Langone Hospital.
Vist novoslabs.com and use code NAT5 to save.
Thank you to our sponsors for making this episode possible:
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Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance
Instagram: https://www.instagram.com/nathalieniddam/
Website: NatNiddam.com
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community
Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08
Find more from Chris:
Instagram: instagram.com/slowmyage/
Twitter: twitter.com/slowmyage
Website: slowmyage.com
What we discuss:
(0:03:00) - The Short-Term Health vs. Longevity Dilemma
(0:10:34) - Balancing Strategies for Longevity
(0:19:29) - Aging and Anti-Aging Formulations
(0:28:32) - Autophagy and Microbiome in Aging
(0:39:26) - Understanding Senescent Cells-Safest Approach
(0:53:55) - Comparing Different Aging Clocks
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