Dhru Purohit Show cover image

Dhru Purohit Show

Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention

Feb 3, 2025
In this insightful discussion, Dr. David Perlmutter, a board-certified neurologist and bestselling author, shares critical lifestyle strategies for preventing Alzheimer's, emphasizing the importance of blood sugar regulation and dietary choices. Dr. Lisa Mosconi, a neuroscience professor and director of the Women’s Brain Initiative, reveals how menopause impacts women's brain health and its connection to Alzheimer’s. Together, they explore the gut-brain connection, the effects of fructose, and personalized nutrition, highlighting ways to support cognitive function throughout life.
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Podcast summary created with Snipd AI

Quick takeaways

  • Maintaining stable blood sugar levels is essential for preventing cognitive decline and diseases like Alzheimer's by supporting brain energetics.
  • Lifestyle choices, particularly in diet and physical activity, significantly influence Alzheimer's risk, even for those with genetic predispositions.

Deep dives

The Impact of Blood Sugar on Brain Health

Maintaining stable blood sugar levels is crucial for brain health and can play a significant role in preventing cognitive decline and diseases like Alzheimer's. Insulin is the key hormone that helps regulate blood sugar by allowing glucose to enter cells, including those in the brain, essential for their energy supply. However, insulin resistance can compromise brain energetics and is often linked to high blood sugar levels, which can promote inflammation—a central player in Alzheimer's disease progression. The choices that individuals make regarding diet, exercise, and sleep all contribute to blood sugar levels, highlighting the importance of lifestyle factors in managing brain health.

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